منابع مشابه
Radiation-Induced Oral Mucositis
Radiation-induced oral mucositis (RIOM) is a major dose-limiting toxicity in head and neck cancer patients. It is a normal tissue injury caused by radiation/radiotherapy (RT), which has marked adverse effects on patient quality of life and cancer therapy continuity. It is a challenge for radiation oncologists since it leads to cancer therapy interruption, poor local tumor control, and changes i...
متن کاملCancer treatment-induced oral mucositis.
Oral mucositis is one of the main complications in non-surgical cancer treatments. It represents the major dose-limiting toxicity for some chemotherapeutic agents, for radiotherapy of the head and neck region and for some radiochemotherapy combined treatments. Many reviews and clinical studies have been published in order to define the best clinical protocol for prophylaxis or treatment of muco...
متن کاملUse of palifermin for the prevention of high-dose methotrexate-induced oral mucositis.
BACKGROUND Oral mucositis is a frequent problem after high-dose methotrexate (HD-MTX), impairing patient's quality of life, leading to higher rates of infections and delaying subsequent chemotherapy. This report describes the effect of palifermin in patients treated within the GMALL-B-ALL 2002 protocol containing HD-MTX who developed a severe mucositis in cycle A1/B1. PATIENTS AND METHODS Ten...
متن کاملPreliminary histological analysis of methotrexate-induced oral mucositis: experimental study in mice
144 Objective: This in vivo experimental study evaluated the effect of methotrexate on the oral mucosa of mice. Methodology: A total of 28 adult BALB/c mice were randomly assigned into a control and an experimental group. Mice in the experimental group were immunosuppressed with 2.5 mg/kg of methotrexate for three consecutive days. One mouse from each group was sacrificed each day for 10 days. ...
متن کاملThe effect of hippophae rhamnoides extract on oral mucositis induced in rats with methotrexate
Objective: To investigate the effect of HRE (Hippophae rhamnoides extract) on oral mucositis induced in rats with MTX. Material and Methods: Experimental animals were divided into groups as healthy (HG), HRE+MTX (HMTX), and control group, which received MTX (MTXC). HMTX group received 50 mg/kg HRE while MTXC and HG groups received equivolume distilled water with gavage once a day. After one h...
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ژورنال
عنوان ژورنال: Journal of Oral Medicine and Pain
سال: 2015
ISSN: 2288-9272
DOI: 10.14476/jomp.2015.40.2.82